A Board of Directors with deep expertise in infectious disease, drug development, innovative financing models, and biopharmaceutical senior management roles advises the Appili leadership team.
Ian Mortimer has over 20 years of experience in the biotechnology sector. He is currently President and Chief Executive Officer of Xenon Pharmaceuticals Inc. (NASDAQ: XENE), a company developing innovative therapeutics to improve the lives of patients with neurological disorders. Prior to joining Xenon in 2013 as Chief Financial Officer, Mr. Mortimer spent six years at Tekmira Pharmaceuticals Corporation, now Arbutus Biopharma Corporation (NASDAQ: ABUS), as Executive Vice President and Chief Financial Officer. He led both Xenon’s and Tekmira’s listings on the NASDAQ, in 2014 and 2010 respectively. From 2004 to 2007, Mr. Mortimer was Chief Financial Officer of Inex Pharmaceuticals Corporation. Mr. Mortimer has an M.B.A. from Queen’s University, a B.Sc. in Microbiology from the University of British Columbia, and is a Chartered Professional Accountant, Certified Management Accountant.
Brian Bloom co-founded Canada’s leading healthcare investment banking firm, Bloom Burton & Co. in 2008, and serves as Bloom Burton’s chairman and CEO. Brian also serves on the Board of Directors of Appili Therapeutics, Triumvira Immunologics, Satellos Bioscience and Qing Bile Therapeutics. Brian was formerly the Chairman of the Board of Grey Wolf Animal Health, a member of the Life Sciences Advisory Board at the National Research Council of Canada, the Dean’s Advisory Board at McMaster University and on the Board of Directors of BIOTECanada and the Baycrest Foundation.
Prior to Bloom Burton, Brian spent six years at Dundee Securities in the healthcare and biotechnology institutional sales and equity research groups. Brian started his career at New York-based investment banking firms SCO Financial Group and Molecular Securities. Brian received an Honors Bachelor of Science in Biochemistry from McMaster University and subsequently studied at the Mount Sinai Graduate School for Biological Sciences of New York University, with a focus in molecular endocrinology and biophysics. Brian is the proud recipient of the McMaster University 2017 Distinguished Alumni Award in Science.
Juergen Froehlich, MD
Dr. Froehlich’s career spans multiple decades and covers a broad range of drug development successes. It includes strategic planning and execution of all phases of drug development and regulatory interactions across therapeutic areas such as cystic fibrosis, bronchiectasis, and hepatitis C. He has worked with biologics, peptides, small molecules and RNA therapeutics at companies including Boehringer Ingelheim, Genentech, Quintiles, Bristol-Myers-Squibb, Ipsen, Vertex, Aradigm Corporation, EnBiotix, Genevant and Spexis AG. He was instrumental in obtaining successful marketing authorizations worldwide, including the U.S., Canada, and the E.U. As Chief Medical Officer and Head of Regulatory Affairs of Aradigm Corporation, he conducted a Ph 3 trial program with a liposomal formulation of ciprofloxacin for inhalation in patients with non-cystic fibrosis bronchiectasis (NCFBE) and chronic Pseudomonas aeruginosa (PA) lung infections. Currently, as Chief Medical and Development Officer of Spexis AG, he is overseeing early and late-stage development activities for inhaled Colistin and inhaled Murepavadin to treat chronic PA lung infection, and is involved in preclinical activities, supported by the CARB-X funding, to identify novel antibiotics overcoming antibiotic resistance. He was an invited panel member at a U.S. Food and Drug Administration workshop in 2018 for inhaled antibiotics in cystic fibrosis and NCFBE.
Theresa Matkovits, PhD
Dr. Theresa Matkovits has more than 20 years of experience as a leader in global drug development and commercialization, with extensive expertise in infectious disease. She currently serves as the Chief Development Officer at Matinas Biopharma where she serves as an Executive Leadership Team member, joining the company in October 2018. Dr. Matkovits is responsible for leading the Global Development efforts of the company’s development pipeline products, including their Infectious Disease products. Prior to this role, she was the Chief Operating Officer at ContraVir (Nasdaq: CTRV) now Hepion, where she led global development of the company’s clinical-stage antiviral portfolio. She also served as ContraVir's Executive Vice President, Head of Drug Development, where she was responsible for leading all global drug development functional areas for the company's infectious disease programs. Dr. Matkovits’ career also includes steering the clinical development and approval efforts for Natpara® at NPS Pharmaceuticals; serving as a Vice President and Innovation Leader at The Medicines Company (Nasdaq: MDCO), where she managed global development and commercialization efforts for the Company’s infectious disease franchise; and several leadership positions at Novartis in its U.S. Medical and Drug Regulatory Affairs and Global Development Divisions. Dr. Matkovits is a member of the Board of Directors for BioSurplus and Good Cap Pharmaceuticals, and previous director of Aradigm Corporation (Nasdaq: ARDM). Dr. Matkovits earned her PhD in Biochemistry and Molecular Biology from the University of Medicine and Dentistry of New Jersey - New Jersey Medical School.
Rochelle Stenzler has more than 25 years of experience as a board director and senior operating executive in healthcare and other industries. A pharmacist by education and training, Ms. Stenzler has served as Board Chair of Spartan Bioscience since August 2020. Prior to this role, she served as Board Chair of Cynapsus Therapeutics, until it was acquired for C $841M by Sunovion Pharmaceuticals in 2016. She has previously served as a Board Director & Vice Chair of Humber River Hospital; President & CEO of TouchLogic Corporation; President, International Operations of TLC Laser Eye Centers; President, Revlon Canada; and President and General Manager of Pharma Plus Drugmarts Ltd.
Ms. Stenzler also has extensive corporate governance experience, which includes serving as a member of the Spartan Bioscience Finance, Audit and Risk Committee; Vice-Chair and Chair of the Nominating, Governance, and Human Resources Committee of the Humber River Hospital in Toronto; and as an Advisory Board member to Social Capital Partners. Ms. Stenzler is a graduate of the University of Toronto with a BSc.Phm. and a Gold Medal in Compounding and Dispensing, and the Rotman School of Management, Institute of Corporate Directors, with an ICD.D.
Armand Balboni, MD, PhD
Armand Balboni's career includes medical research and drug development experience in civilian, academic and military organizations, most recently as a partner at Bloom Burton & Co. where he was the firms senior advisor for regulatory and medical affairs. As an active duty military officer, Dr. Balboni served as a staff officer at the U.S. Army Research Institute of Infectious Diseases (USAMRIID). He completed a military staff fellowship at the U.S. Food and Drug Administration and went on to serve as the deputy director of clinical and regulatory affairs for the U.S. Army. Armand completed his doctoral work in the MD/PhD program at the Icahn School of Medicine at Mount Sinai and earned his law degree at Brooklyn Law School.